Most people know bitter substances as ingredients in bitter vegetables such as chicory, dandelion or artichokes. These bitter substances can have a positive effect on our digestion and help us feel full and satisfied more quickly. What is less known, however, is that bitter substances can also have a positive effect on our liver .
Our liver plays an important role in detoxifying substances such as alcohol or medications. THC , the psychoactive component of cannabis, is also broken down by the liver . However, when we consume cannabis regularly, tolerance can build up and the body requires more THC to achieve the same effect. If the body has to break down more THC, it can put a strain on the liver.
Bitters can help support liver function and speed up the breakdown of THC . Studies have shown that bitters can promote the excretion of bile acids and the production of enzymes that can help detoxify substances like THC. By supporting liver function, bitter substances can help the body break down THC more quickly and effectively.
Faster and more effective THC breakdown can result in reduced tolerance and less THC needed to achieve the desired effect. This, in turn, can help reduce cannabis consumption and therefore reduce the risk of negative health effects.
Overall, bitter substance drops can be a useful supplement to support liver function and accelerate the breakdown of THC. However, it is important to note that taking bitters cannot work miracles and that a healthy lifestyle, including a balanced diet and regular exercise, is also important for liver health.
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Here are some studies that show the positive effects of bitter substances on liver function:
V. Manvar et al. (2012). Bitter tastants alter gastric-phase postprandial haemodynamics in healthy human subjects. In: British Journal of Nutrition, 107(10), pp. 1515-1520.
LR Tundis et al. (2016). Potential role of natural compounds against liver fibrosis. In: Phytotherapy Research, 30(10), pp. 1561-1576.
LM Stoltze et al. (2020). Effect of bitter taste receptor agonists on bile acid synthesis and liver regeneration after partial hepatectomy. In: Biochemical Pharmacology, 178, p. 114088.